There is an infection that is especially common in young animals housed in groups (in shelters, rescue areas, kennels, etc.) It is called Coccidia, and while it’s a common parasite. it is not necessarily a sign of poor animal husbandry.
Coccidia are single-celled organisms that infect the intestine. They are microscopic parasites detectable on routine fecal tests in the same way that worms are, but coccidia are not worms. And, they are not susceptible to deworming medications. They are also not visible to the naked eye. Coccidia infection causes watery diarrhea that is sometimes bloody and can be a life-threatening problem to an especially young or small pet. There are many different species of coccidia but for dogs and cats, the most common infections are with coccidia of the genus Cystoisospora. Dogs and cats each have their own coccidia species and cannot infect each other, nor can they infect people.
Oocysts are passed in the stool. In an outside environment the oocysts begin to mature leaving them able to infect a new host. It only takes 12 to 36 hours for an oocyst to become infective and after that, any host that accidentally swallows the oocyst will probably be infected. Because the oocyst becomes infective in such a short time, it is important to remove stool as quickly as possible so that the pet's environment does not become contaminated with infective oocysts. Oocysts can also be swallowed by mice, flies, cockroaches, or other insects. A dog or cat can be infected by eating an animal carrying an oocyst.
The oocyst breaks open and releases eight sporozoites. These eight sporozoites go on to infect intestinal cells and, once inside these cells, they divide rapidly over and over until a new stage called a merozoite results. The merozoites divide and reproduce rapidly, filling up the intestinal cell until it bursts. A multitude of merozoites are released when the cell bursts and they go on to infect and similarly destroy more and more intestinal cells. When enough intestinal cells are destroyed, in three to 11 days, bloody watery diarrhea and disease result.
A routine fecal test should be performed for any new puppy or kitten whether there are signs of diarrhea or not as youngsters are commonly parasitized. This test is also a good idea for any patient with diarrhea and is recommended at least once a year for healthy dogs and cats as a screening test.
Coccidia are microscopic and a test such as this is necessary for diagnosis. Small numbers of coccidia can be hard to detect, so just because a fecal sample tests negative, this doesn’t mean the pet isn’t infected. Sometimes several fecal tests are performed, especially in a young pet with refractory diarrhea (one that won’t go away); parasites may not be evident until later during the condition.
There are two common treatments used for Cystoisospora infections in pets: sulfa drugs (the traditional treatment) and coccidiocidal medications (newer treatment). The most common medicines used against coccidia are called coccidiostats. They inhibit coccidial reproduction. Once the numbers stop expanding, it is easier for the patient’s immune system to catch up and wipe out the infection. This also means, though, that the time it takes to clear the infection depends on how many coccidia organisms there are to start with and how strong the patient’s immune system is. A typical treatment course lasts about a week or two, but it is important to realize that the medication should be given until the diarrhea resolves plus an extra couple of days. Medication should be given for at least five days in total. Sometimes courses need to be given for a month. In dogs and cats, sulfa-based antibiotics are the most used coccidiostats.
There are newer medications that actually kill the coccidia outright: ponazuril and toltrazuril, both actually being farm animal products that can be compounded into concentrations more appropriate for dogs and cats.
These medications can curtail a coccidia infection in only a few doses and have been used in thousands of shelter puppies and kittens with no adverse effects. Their use is becoming more popular used in kennels, catteries, and animal shelters and you may be pleasantly surprised to find one of them in stock at your regular veterinary office.
Decontaminating the home environment may also be recommended by your veterinarian. Since the oocysts are resistant to most disinfectants, prompt removal of all stool, then scrubbing any soiled areas with a detergent, will be the best environmental measure.
Dr. Lamb is the Veterinarian at the Manchester Animal Hospital.
